restriction fragment length polymorphism
- restriction fragment length polymorphism
(RFLP)
The different length fragments of DNA produced by the action of a restriction enzyme at a specific polymorphic site. If the restriction endonuclease recognizes the variable site, then two fragments are produced; if not, only one is formed. An individual may be homozygous or heterozygous, that is, the site may be present or absent on both chromosomes of the homologous pair, or it may be present on one and absent on the other. It should also be noted that different fragment lengths are produced if distance between the fixed recognition sites changes. This can occur because of the insertion or deletion of nucleotides or because of a variable number of tandem repeats.
Forensic science glossary.
John C. Brenner .
2012.
Look at other dictionaries:
restriction fragment length polymorphism — n variation in the length of a restriction fragment produced by a specific restriction enzyme acting on DNA from different individuals that usu. results from a genetic mutation (as an insertion or deletion) and that may be used as a genetic… … Medical dictionary
Restriction Fragment Length Polymorphism — n. The older and more discriminating form of DNA testing. Restriction Fragment Length Polymorphism is a process that breaks DNA strands into tiny fragments at specific points on the DNA chain. Also known as HLA DQ Alpha, or simply DQ Alpha.… … Law dictionary
restriction fragment length polymorphism — restriction fragment length polymorphism. См. ПДРФ. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
Restriction fragment length polymorphism — A Restriction fragment length polymorphism (or RFLP, often pronounced as rif lip ) is a variation in the DNA sequence of a genome that can be detected by breaking the DNA into pieces with restriction enzymes and analyzing the size of the… … Wikipedia
Restriction Fragment Length Polymorphism — Restriktionsfragmentlängenpolymorphismus, abgekürzt RFLP (sprich: Riflip , von engl.: Restriction Fragment Length Polymorphism, auch PLP: PCR Längen Polymorphismus) bezeichnet Unterschiede von DNA Sequenzen homologer Chromosomen, welche als… … Deutsch Wikipedia
Terminal restriction fragment length polymorphism — (TRFLP or sometimes T RFLP) is a molecular biology technique for profiling of microbial communities based on the position of a restriction site closest to a labeled end of an amplified gene. The method is based on digesting a mixture of PCR… … Wikipedia
restriction fragment length polymorphism — Abbreviation: RFLP A class of genetic marker based on the detection of variation in the length of restriction fragments generated when DNA is treated with restriction endonucleases. Differences in fragment lengths arise due to genetic variation… … Glossary of Biotechnology
restriction fragment length polymorphism — noun Date: 1982 variation in the length of a DNA fragment produced by a specific restriction enzyme acting on DNA from different individuals that usually results from a genetic mutation and that may be used as a genetic marker … New Collegiate Dictionary
restriction fragment length polymorphism — noun : variation in the length of a DNA fragment produced by a specific restriction enzyme acting on DNA from different individuals that usually results from a genetic mutation (as an insertion or deletion) and that may be used as a genetic… … Useful english dictionary
restriction fragment length polymorphism — (= RFLP) Technique, also known as DNA fingerprinting, that allows familial relationships to be established by comparing the characteristic polymorphic patterns that are obtained when certain regions of genomic DNA are amplified (typically by PCR) … Dictionary of molecular biology
